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Talk:Cyclooxygenase-2 inhibitor

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Needs better balance

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This article passes over much of the information about COX-2 inhibitors quickly, then spends the bulk of its wordage on *potential* uses + controversy/fraud/etc and I find this odd. It ought to look more like the wikipedia entry for NSAID with a more thorough introductory description, examples, uses, mechanism of action, adverse effects, contraindications. I don't have the time or energy to do this hence I'm just adding my 2 cents to the talk page.Niccast (talk) 23:31, 19 March 2020 (UTC)[reply]

Wiki Education assignment: Biochemistry II

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 17 January 2022 and 20 May 2022. Further details are available on the course page. Student editor(s): Cayley P (article contribs).

Apoptosis

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The last two paragraphs reference apoptosis, a well known biological function of programmed cell death. But the wording is a little too dramatic, in my opinion:

"Coxibs such as Celebrex (celecoxib), by selectively inhibiting the overexpressed COX-2, allow p53 to work properly. Functional p53 allows DNA damaged neuroblastoma cells to commit suicide through apoptosis, halting tumor growth."

Also, this really ought to link to apoptosis, rather than suicide. ThreeRocks (talk) 03:05, 30 September 2022 (UTC)[reply]